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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 28.79
Human Site: S628 Identified Species: 42.22
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 S628 K L L K L K E S T E R T V S K
Chimpanzee Pan troglodytes XP_518055 1227 139177 S621 K L L K L K E S T E R T V S K
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S628 K L L K L K E S T E R T V S K
Dog Lupus familis XP_549061 1234 139874 S629 K L L K L K E S T E H T V S K
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S629 K L L K L K E S T E H T V S K
Rat Rattus norvegicus Q7M6Z5 1394 158861 N749 E L I K T G D N A K S V S R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S634 K L L K L K E S T E R T V S K
Frog Xenopus laevis Q91784 1226 138905 S631 K L L K L R E S T E K T V A K
Zebra Danio Brachydanio rerio Q58G59 1363 154819 E733 I T I R M K E E L I K E L V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 L275 K E A S K I N L A L S S L G N
Honey Bee Apis mellifera XP_395595 1064 123475 V549 L K N S S Q I V D Y S K E I Q
Nematode Worm Caenorhab. elegans P46873 699 78760 N190 E L M T R G F N N R H V G A T
Sea Urchin Strong. purpuratus P46872 699 78679 D190 A F V V N N A D D M D R I M T
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 S534 R R L E E K E S E M K L F G G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 A613 E G L R H N L A S I P S G P G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 P419 P E S R A E T P A I S D R A G
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 100 100 93.3 N.A. 93.3 13.3 N.A. N.A. 100 80 20 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 53.3 N.A. N.A. 100 100 53.3 N.A. 20 13.3 33.3 13.3
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 26.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 46.6 N.A. N.A. 40 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 7 0 7 7 19 0 0 0 0 19 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 7 13 0 7 7 0 0 0 % D
% Glu: 19 13 0 7 7 7 57 7 7 44 0 7 7 0 0 % E
% Phe: 0 7 0 0 0 0 7 0 0 0 0 0 7 0 0 % F
% Gly: 0 7 0 0 0 13 0 0 0 0 0 0 13 13 19 % G
% His: 0 0 0 0 7 0 0 0 0 0 19 0 0 0 0 % H
% Ile: 7 0 13 0 0 7 7 0 0 19 0 0 7 7 0 % I
% Lys: 50 7 0 50 7 50 0 0 0 7 19 7 0 0 50 % K
% Leu: 7 57 57 0 44 0 7 7 7 7 0 7 13 0 0 % L
% Met: 0 0 7 0 7 0 0 0 0 13 0 0 0 7 0 % M
% Asn: 0 0 7 0 7 13 7 13 7 0 0 0 0 0 7 % N
% Pro: 7 0 0 0 0 0 0 7 0 0 7 0 0 7 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 13 % Q
% Arg: 7 7 0 19 7 7 0 0 0 7 25 7 7 7 0 % R
% Ser: 0 0 7 13 7 0 0 50 7 0 25 13 7 38 0 % S
% Thr: 0 7 0 7 7 0 7 0 44 0 0 44 0 0 13 % T
% Val: 0 0 7 7 0 0 0 7 0 0 0 13 44 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _